姓名：李金霞   
职称：副研究员 
Tel/Fax：+86-10-88236786  
Email: lijinxia@ihep.ac.cn 
    

 

个人情况简介： 
2007年7月毕业于南京医科大学，获学士学位；2012年毕业于北京大学医学部，获博士学位，主要研究稀土化合物药理与毒理作用及其细胞与分子机制；2012年7月加入中国科学院高能物理研究所（纳米生物效应与安全性重点实验室）担任助理研究员，主要评估高效抗肿瘤纳米药物金属富勒醇Gd@C₈₂(OH)₂₂的潜在毒理；2018年8月至今担任副研究员，研究内容为纳米材料的生物学效应及安全性评价。

研究方向： 
（1）  生物医用纳米材料的生物学效应及其作用机理研究； 
（2）  环境中纳米物质的毒理研究及其干预措施； 
（3） 用同步辐射技术研究纳米材料与生物大分子的相互作用； 

近期代表性论文： 
（1）Xia S, Li J, Zu M, Li J, Liu J, Bai X, Chang Y, Chen K, Gu W, Zeng L, Zhao L, Xing G*, Xing G*,Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and FXa，Nanomedicine,2018,14:929-939 
（2）Jinxia Li#, Xueqing Xing#, Baoyun Sun, Yuliang Zhao*, Zhonghua Wu*, Metallofullerenol inhibits cellular iron uptake by inducing transferrin tetramerization, Chem. Asian J., 2017, 12(20):2646-2651 
（3）Jinxia Li, Liming Wang, Feng Zhao*,Epigenetics-based individual interventions against the health risks of PM2.5,Sci. Bull, 2017, 62(11):743-744 
（4）Jinxia Li, Yuliang Zhao*, Nanotechnology in the programmed cell therapy: nowhere to escape of cancer, Sci. Bull, 2016, 61(1): 45-47 
（5）Jinxia Li, Feng Zhao, Chunying Chen*, The new face of iron oxide nanoparticles: the bullets targeting tumor microenvironment for cancer therapy, Sci. Bull, 2016, 61(23)：1788-1790 
（6）Jinxia Li*, Nanotechnology-based platform for early diagnosis of cancer, Sci. Bull, 2015，60(4)：488-490 
（7）Zhang X, Tian G,* Yin WY, Wang LM, Zheng XP , Yan L, Li JX, Su HR, Chen CY, Gu ZJ* and Zhao YL*,Controllable generation of nitric oxide by near-infrared sensitized upconversion nanoparticles for tumor therapy, Adv. Funct. Mater., 2015, 25, 3049–3056 
（8）Feng M, Fan YZ, Ma XJ, Li JX , Yang XG*, The gadolinium-based contrast agent Omniscan？ promotes in vitro fibroblast survival through in situ precipitation, Metallomics, 2015,7, 1103-1110  
（9）Jinxia Li , Xueling Chang , Xiaoxia Chen, Zhanjun Gu, Feng Zhao* , Zhifang Chai, Yuliang Zhao, Toxicity of inorganic nanomaterials in biomedical imaging, Biotechnol Adv, 2014, 32, 727-743  
（10）Pan X, Li JX, Wang K, Yu S*, Lanthanum chloride promotes proliferation of NIH3T3 cells via cell cycle machinery,JCPS,2013. doi:10.5246/jcps.2013.01.008