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2026年论文
2026-04-13 | 浏览次数: | 文章来源: | 【大 中 小】

1. Qin, M.; Zhang, Z.; Zhao, Y.; Meng, H. Enhanced Transcytosis and Retention (ETR) of Drug Delivery Nanocarrier in Solid Tumors. Accounts of Chemical Research 2026, DOI: 10.1021/acs.accounts.6c00062

2. Li, Z.-Y.; Hu, S.-Y.; Xu, G.-Y.; Huang, J.-X.; Yang, X.-Y.; Wei, T.-C.; Feng, J.-Q.; Yuan, J.-X.; Li, C.-R.; Li, Y.-T.; et al. Targeted Neutrophil Extracellular Traps Mimics Combat <i>Staphylococcus aureus</i> Infections. Acs Infectious Diseases 2026, DOI: 10.1021/acsinfecdis.5c00831

3. Hu, M.; He, Y.; Wu, L.; Su, W.; Zhang, W.; Yu, X.; Guo, M.; Li, Y.; Lu, H.; Chen, C.; et al. Chiral Polyproline Enables Functional Stealth for Simultaneous Long Circulation and Endoplasmic Reticulum-Targeted Antigen Presentation. Acs Nano 2026, 20 (9), 7908-7927, DOI: 10.1021/acsnano.5c21970

4. Song, R.; Cen, J.; Cai, R.; Yao, C.; Shi, Q.; Zhang, Y.; Song, C.; Tan, J.; Hou, M.; Li, R.; et al. Holistic and Multivalent Engineering of In Vivo Nanomedicine Reactions for Enhanced Multistage Tumor Delivery. Acs Nano 2026, 20 (3), 3048-3065, DOI: 10.1021/acsnano.5c19431

5. Tang, M.; Lv, W.; Gao, X.; Xu, C.; Zhang, T.; Liang, B.; Zhao, X.; Liao, H.; Du, C.; Li, X.; et al. Immunological Conversion of Solid Tumors Using an Outer Membrane Vesicle Based Checkpoint Nanoinhibitor for Cancer Immunotherapy. Acs Nano 2026, 20 (6), 4710-4721, DOI: 10.1021/acsnano.5c14341

6. Xie, X.; Liu, G.; Zhang, Y.; Yang, Y.; Niu, W.; Lin, O.; Bian, Y.; Lu, J.; Zhang, S.; Tang, A. Spectral Narrowing of Ag-In-Ga-S Nanocrystals Enabled by Component Engineering. Acs Nano 2026, 20 (3), 2812-2820, DOI: 10.1021/acsnano.5c17528

7. Yang, J.; Yang, M.; Wang, Z.; Luo, X.; Peng, B.; Yan, R.; Lv, L.; Wan, J.; Chen, K.; Chang, Y.-N.; et al. Structure-to-Therapeutic Transformation of Nanohydrogels Triggers Calcium Overload for Potentiated Boron Neutron Capture Therapy. Acs Nano 2026, 20 (8), 7321-7332, DOI: 10.1021/acsnano.5c22264

8. Yang, K.; Li, B.; Jiang, A.; Shi, X.; Nie, G.; Xiao, B. Design Principles of Oral Nanomedicines to Overcome the Delivery Barriers. Acs Nano 2026, 20 (4), 3175-3204, DOI: 10.1021/acsnano.5c14045

9. Zargul, A.; Liu, H.; Zhang, W.; Wang, H.; Liu, J.; Chen, C. Advances in Pathogen Detection by Nanosensors: Biorecognition Strategies, Signal Amplification, and Platform Engineering. ACS nano 2026, DOI: 10.1021/acsnano.5c22148

10. Zhang, S.-L.; Yu, F.-C.; Guan, Y.-H.; Liu, J.-A.; Wu, X.-H.; Yang, Z.-X.; Qiao, Z.-Y.; Wang, H. In Vivo Programmed Assembly of Polymer-Peptide Conjugates to Overcome Multistage Drug Delivery Barriers. Acs Nano 2026, 20 (7), 6176-6185, DOI: 10.1021/acsnano.5c20521

11. Zhao, Y.; Liu, C.; Zhang, X.; Gu, T.; Wang, Y.; Zuo, T.; Liu, S.; Xu, X.; Meng, H. Mechanistic and Strategic Insights into How Lipid Nanoparticles Interact with Membrane-Based Biological Barriers. ACS nano 2026, DOI: 10.1021/acsnano.5c21857

12. Zhang, X.; Dai, Y.; Yuan, Y.; Yang, L.; Yang, X.; Ma, T.; Wang, M.; Yang, Z.; Hu, R.; Wang, Z.; et al. Urchin-Like Sulfate Radical Nano-Generator Based on MoS₂/Bi₂S₃ Heterostructure for Enhanced Anticancer Therapy. Advanced Functional Materials 2026, 36 (6), DOI: 10.1002/adfm.202507883

13. Tang, L.; Liu, H.; Feng, J.; Yao, Y.; Cao, Y.; Yin, Y.; Fu, C.; Gao, J.; Xiao, Q.; Yan, Z.; et al. Site-Specific Antibacterial Strategy for Multi-Pathway Treatment of Drug-Resistant Skin Infections. Advanced Healthcare Materials 2026, 15 (5), DOI: 10.1002/adhm.202504240

14. Kang, Y.; Han, X.; Zhou, S.; Wang, X.; Wang, Y.; Song, P.; Su, X.; Qin, M.; Qian, D.; Meng, H.; et al. Engineered Apoptotic Extracellular Vesicles for Programmable Regulation of Neutrophil-Macrophage-ROS Pathogenic Axis to Reconstruct Rheumatoid Arthritis Microenvironment. Advanced Materials 2026, 38 (3), DOI: 10.1002/adma.202508072

15. Liu, S.; Li, B.; Yang, Q.; Zu, M.; Xu, H.; Li, B.; Li, P.; Zhang, J.; Li, L.; Zhu, Z.; et al. Pathology-Driven Design of a Biomimetic Ferromagnetic Nanomedicine for Dual-Mode Treatment of Ulcerative Colitis and Colitis-Associated Colorectal Cancer. Advanced Materials 2026, 38 (6), DOI: 10.1002/adma.202514413

16. Xu, H.; Li, T.; Li, M.; Zhang, J.; Zhang, Z.; Weng, Y.; Luo, D.; Yang, C.; Guo, J.; Liu, Y.; et al. Modular Assembly of Lipid Nanoparticles for Targeted mRNA Therapeutics and Vaccines. Advanced Materials 2026, 38 (15), DOI: 10.1002/adma.202509199

17. Lv, N.; Chen, P.; Dai, X.; Xu, H.; Li, Z.; Shan, Z.; Li, J.; Guo, F.; Chen, Y.; Li, J.; et al. IgG-Bridging-Seeded Synergistic Aggregation of SARS-CoV-2 Spikes Underlies Potent Neutralization by a Low-Affinity Antibody. Advanced Science 2026, 13 (11), DOI: 10.1002/advs.202517192

18. Ma, W.; He, Q.; Sun, J.; Chen, Y.; Su, H.; Zhang, L.; He, X.; Wang, Y.; Xie, C.; Zhang, Z.; et al. Engineering Dimensional Configuration of Single-Atom S-Cu-S Sites as Reversible Electron Station for Enhanced Peroxidase-Mimicking. Advanced Science 2026, 13 (7), DOI: 10.1002/advs.202510133

19. Zhang, J.; Huang, X.; Ma, L.; Chen, Z.; Li, T.; Wang, L.; Guo, Y.; Xu, H.; Li, J.; Qin, J.-j.; et al. Micro-Organ Chip Deciphers Tumor-Derived G-CSF as Remote Commander of Lung Pre-Metastatic Niche via VEGFA-KDR Cascade. Advanced Science 2026, 13 (7), DOI: 10.1002/advs.202518584

20. Wu, B.; Yi, X.; Zhao, J.; Li, L. An Orthogonal Nucleic Acid/Peptide Amplification Circuit Enables Protease-Triggered, Cancer Cell-Selective PD-L1 Imaging. Angewandte Chemie-International Edition 2026, 65 (4), DOI: 10.1002/anie.202520284

21. Zhang, N.-Y.; Wen, Z.; Cai, M.-Z.; Zhou, K.-T.; Li, H.-Z.; Liu, Y.-X.; Wu, S.; Xia, Y.; An, H.-W.; Wang, H. De Novo Design of Hexamer-Linker Dual-Action Nano-PROTAC for Tumor-Specific Ferroptosis. Angewandte Chemie-International Edition 2026, 65 (2), DOI: 10.1002/anie.202509924

22. Su, K.; Yan, Y.; Huang, J.; Chen, Y.; Shang, X.; Wang, X.; Liu, Y.; Lai, Z.; Song, F.; Zhang, Z.; et al. Mitochondrial-targeted injectable hydrogel for periodontitis therapy via oral immunity and flora regulation. Bioactive Materials 2026, 58, 348-369, DOI: 10.1016/j.bioactmat.2025.12.002

23. Zhang, X.; Wang, X.; Xu, M.; Yuan, J.; Liu, Y. Monocyte/macrophage-mediated trained immunity in disease prevention and immunotherapy. Bioactive Materials 2026, 59, 745-762, DOI: 10.1016/j.bioactmat.2025.12.044

24. Choy, O. T.; Fletcher, N. L.; Fu, C.; Vu, M. N.; Ediriweera, G. R.; Humphries, J.; Hu, M.; Kent, S. J.; Cai, R.; Chen, C.; et al. PEG-free Lipid Nanoparticles for mRNA Delivery: Superhydrophilic Sulfoxide Polymer Coatings. Biomacromolecules 2026, 27 (1), 624-639, DOI: 10.1021/acs.biomac.5c01899

25. Hou, D.-Y.; Li, X.-P.; Wang, Y.-Z.; Zhang, P.; Wu, J.-C.; You, H.-H.; Lv, M.-Y.; Zhou, S.-A.; Liu, X.; Zhang, G.; et al. Translational contrast agents for use in fluorescence image-guided tumor surgery. Biomaterials 2026, 325, 123549, DOI: 10.1016/j.biomaterials.2025.123549

26. Li, Y.-T.; Wei, T.-C.; Yuan, J.-X.; Feng, J.-Q.; Yang, P.-P.; Tang, S.-S.; Wang, L.; Wang, H. Biomimetic antimicrobial peptides against gram-positive bacteria. Biomaterials 2026, 329, 123916, DOI: 10.1016/j.biomaterials.2025.123916

27. Ma, H.; Li, X.; Li, J.; Bu, J.; Li, X.; Zhang, J.; Yu, S.; Nie, G.; Wang, H.; Feng, H. Generation of patient-derived sarcoma organoids for personalized drug screening and precision cancer immunotherapy. Biomaterials 2026, 324, 123546, DOI: 10.1016/j.biomaterials.2025.123546

28. Ma, X.-Q.; Wang, L.-Y.; Zhang, Y.-X.; Zhang, N.-Y.; Li, H.-Z.; Liang, J.-X.; Liao, Y.-S.; An, H.-W.; Zhang, X.-L.; Wang, H. A self-assembled fluorescent contrast agent for imaging-guided simultaneous resection of breast tumors and metastatic lymph nodes in surgery. Biomaterials 2026, 331, DOI: 10.1016/j.biomaterials.2026.124060

29. Zhang, Q.; Lin, L.; Chen, G.; Nie, M.; Chen, G.; Tang, Y.; Chen, H.; Yang, Y.; Yu, Z.; Liang, X.-J.; et al. Disrupting tumor homeostasis with an autoamplificatory nanoinducer to augment pyroptosis for efficient immunotherapy. Biomaterials 2026, 324, DOI: 10.1016/j.biomaterials.2025.123544

30. Zhu, L.; Zu, M.; Wu, F.; Ma, X.; Zhang, S.; Zhang, T.; Li, X.; Yang, H.; Li, Z.; Yu, Z.; et al. Cancer-associated fibroblasts regulating nanomedicine to overcome sorafenib resistance in hepatocellular carcinoma with portal vein tumor thrombus. Biomaterials 2026, 325, DOI: 10.1016/j.biomaterials.2025.123599

31. Hou, D.; Li, X.; Zhang, N.; Fu, X.; Wang, H. Click chemistry-driven tumor theranostics: recent advances, challenges, and future perspectives. Cancer biology & medicine 2026, DOI: 10.20892/j.issn.2095-3941.2025.0667

32. Li, B.; Li, Y.; Zhang, J.; Badama, S.; Zhao, X.; Wang, L.; Zhang, T.; Wang, X.; Yi, X.; Ding, G.-B.; et al. Lysosome-targeting chimeras enable targeted protein degradation. Cell chemical biology 2026, DOI: 10.1016/j.chembiol.2026.01.008

33. Li, B.; Liu, G.; Zhu, Y.; Chen, L.; Zhang, N.; Zhu, X.; Sun, Y.; Liu, X.; Liu, W.; Ma, Y.; et al. Leveraging intratumoral probiotics for pancreatic cancer immunotherapy via xenophagy. Cell host & microbe 2026, DOI: 10.1016/j.chom.2026.02.010

34. Wang, L.-Y.; Liang, J.-X.; Wang, J.; Han, M.; An, H.-W.; Wang, H. Self-assembling peptides construct supramolecular materials. Chemical Communications 2026, 62 (8), 2384-2396, DOI: 10.1039/d5cc06446e

35. Chai, Y.; Yu, Y.; Guo, X.; Tang, J.; Li, H.; Wang, X.; Shen, Z.; Tian, J.; Chen, Y.; Sun, B. Tracking α-phase perovskite crystallization induced by single-crystal seeds for high-performance solar cells. Chemical Engineering Journal 2026, 529, 173193, DOI: 10.1016/j.cej.2026.173193

36. Tan, X.; Ni, Q.; Luo, T.; Nam, K. T.; Cheng, H.-B.; Dyson, P. J.; Liang, X.-J.; Yoon, J. Photoswitchable imaging contrast agents as an emerging frontier in precision bioimaging. Chemical Society Reviews 2026, 55 (5), 2959-2993, DOI: 10.1039/d6cs00003g

37. Chen, Q.-H.; Hou, D.-Y.; Zhang, N.-Y.; Wang, J.-Q.; Zheng, R.; Hu, X.-J.; Wu, X.-H.; Yi, L.; Zhang, Y.-J.; Zhang, G.-X.; et al. Systemic study on anti-tumor activity of HER2 induced peptide-drug conjugate clustering in xenograft tumor models. Chinese Chemical Letters 2026, 37 (5), 111257, DOI: 10.1016/j.cclet.2025.111257

38. Liu, S.; Liang, H.; Lv, L.; Hu, F.; Liu, Q.; Wang, Y.; Zhu, J.; Chen, Z.; Li, J.; Wang, Z.; et al. 3D culture boosting fullerenol nanoparticles to induce calreticulin exposure on MCF-7 cells for enhanced macrophage-mediated cell removal (vol 224, 113204, 2023). Colloids and Surfaces B-Biointerfaces 2026, 257, 115159, DOI: 10.1016/j.colsurfb.2025.115159

39. Bai, S.; Yang, Y.; Sheng, R.; Xu, Y.; Jia, Y.; Li, C.; Zheng, Y.; Li, H.; Li, J. A non-destructive red blood cell retrofit strategy to construct photothermal nanoparticles for cancer therapy. Journal of Colloid and Interface Science 2026, 701, 138754, DOI: 10.1016/j.jcis.2025.138754

40. Zhang, T.; Su, Z.; Liang, S.; Wang, M.; Zhang, M.; Fang, H.; Yao, Y.; Zheng, L.; Xing, X.; Wang, B.; et al. Nanopore-confined photosensitizer in metal-organic frameworks enable enhanced multi-responsive photodynamic activities for efficient tumor cell elimination. Journal of Colloid and Interface Science 2026, 707, 139669, DOI: 10.1016/j.jcis.2025.139669

41. Tian, Y.; Wang, Z.; Li, M.; Luo, X.; Yang, M.; Yang, J.; Peng, B.; Jiang, J.; Li, M.; Liu, J.; et al. A FRET-triggered probe for specific and interference-resistant detection of organophosphorus pesticides by composite Zr-MOFs. Journal of Food Composition and Analysis 2026, 150, 108901, DOI: 10.1016/j.jfca.2026.108901

42. Zhou, Y.; Zhao, X.; Li, M.; Liu, Y.; Wu, Y.; Fan, M.; Cai, S.; Zheng, W.; Wang, L. Plant-derived exosomes: an emerging delivery platform for cancer therapy. Journal of Nanobiotechnology 2026, 24 (1), 195, DOI: 10.1186/s12951-026-04059-0

43. Yu, F.; Zhang, S.; Tao, H.; Jin, H.; Zhao, Y.; Huang, S.-Y.; Li, L. Topology-Informed Design of Circularly Locked DNAzymes Enables Orthogonally Controlled Gene Regulation. Journal of the American Chemical Society 2026, 148 (3), 3365-3374, DOI: 10.1021/jacs.5c18154

44. Zhao, Y.; Chuai, Y.; Fu, K.; Han, Y.; Gao, N.; Nie, G.; Chen, Y. Synthetic biology integrated with material science paves the way for next-generation smart cell therapies. Molecular Therapy Oncology 2026, 34 (1), 201157, DOI: 10.1016/j.omton.2026.201157

45. Weng, Y.; Ren, X.; Li, C.; Cao, Y.; Cai, Y. Recent advances in<i> in</i><i> vivo</i> electroporation technologies for therapeutic and biomedical applications. Nano Research 2026, 19 (3), 94908365 DOI: 10.26599/nr.2026.94908365

46. Zhang, P.; Chang, X.; Dai, C.; Wang, Z.; Guo, Y.; Zhang, S.; Chen, Z.; Guan, Y.; Dang, Z.; Lin, C.; et al. Synergistic "melee attack": Interfacial band-engineered lamellar heterojunction overcome membrane barriers for enhanced antibacterial therapy. Nano Research 2026, 19 (1), 94908265, DOI: 10.26599/nr.2025.94908265

47. He, G.; Huang, Z.; Zong, Y.; Hai, Y.; Zhang, J.; Chen, J.; Chen, H. ZnO nanoparticle-educated exosomes inhibit osteosarcoma metastasis through HIF-1α/miR-1287-5p/Snail axis. Nano Today 2026, 68, 103008, DOI: 10.1016/j.nantod.2026.103008

48. Wang, L.; Tang, J.; Dou, R.; Zhang, H.; Cai, X.; Liu, Y.; Liu, J.; Liu, X.; Zhang, J.; Chen, J. Lactolytic and TGFβ-inhibiting nanoplatform overcomes immunosuppression to enhance radiosensitivity in osteosarcoma. Nano Today 2026, 67, 102953, DOI: 10.1016/j.nantod.2025.102953

49. Zhao, J.; Chen, C.; Hua, H.; Cai, S.; Sun, Q.; Zhang, Q.; Jiang, J.; Cao, M.; Ai, Y.; Zeng, J.; et al. From single-target to multi-target drugs: The significance of formula-derived nanoparticle drug discovery (FDD) as a novel paradigm for complex disease therapy. Nano Today 2026, 68, 103007, DOI: 10.1016/j.nantod.2026.103007

50. Chen, Z.; Wang, Z.; Yang, M.; Yan, R.; Lv, L.; Chang, Y.-n.; Chen, K.; Yang, W.; Yuan, H.; Meng, X.; et al. An <SUP>124</SUP>I-radiolabeled exosome-based treatment platform for enhanced boron neutron capture therapy: precise delivery and real-time PET tracking of boron. Nanoscale 2026, DOI: 10.1039/d5nr04823k

51. Liu, H.; Cao, M.; Zhou, W.; Li, L.; Chen, C. Zinc-selenium synergistic nanoplatform for augmented cancer immunotherapy via trace-elements-mediated immunomodulation. Nanoscale Horizons 2026, DOI: 10.1039/d5nh00372e

52. Zhang, W.; Ghouri, M. D.; Blosi, M.; Liu, Y.; Chen, C.; Cassee, F. R.; Cai, R. A comparative biodistribution and toxicity study of single and multi-component nanomaterials: NMs: TiO2, SiC, and SiC@TiO2. Particle and fibre toxicology 2026, 23 (1), DOI: 10.1186/s12989-026-00664-x

53. Song, X.; Yuan, B.; Zhang, K.; Chen, C.; Zhao, Y.; Mikos, A. G.; Zhang, X. Comparison of innovative medical devices between China and the United States. Regenerative Biomaterials 2026, 13, rbag008, DOI: 10.1093/rb/rbag008

54. Ling, Q.; Li, B.; Feng, Y.; Yang, J.; Wang, S. a.; Li, S.; Zhang, C. Conformation-programmed DNA computing. Science Advances 2026, 12 (8), DOI: 10.1126/sciadv.aec8383

55. Zhao, Y.; Li, R.; Han, Y.; Shi, C.; Lee, K.; Nie, G.; Chen, Y. On-demand cancer immunotherapy via single-cell encapsulation of synthetic circuit-engineered cells. Science Advances 2026, 12 (3), eaea3573, DOI: 10.1126/sciadv.aea3573

56. Guo, M.; Guo, J.-C.; Yao, H.; Gao, F.; Zhao, L.; Cai, L.; Fan, X.; Bao, L.; Li, X.; Zhang, X.; et al. Adjuvant-metal-ion-chelating PTEN mRNA with cell-membrane-coating augments the immune sensitivity for precise cancer immunotherapy. Science Bulletin 2026, 71 (3), 609-622, DOI: 10.1016/j.scib.2025.11.008

57. Xiang, Y.; Wang, F.; Hao, H.; Wang, H.; Xue, J.; Jia, G.; Liu, J.; Li, Z.; Liang, X.-J.; Zhang, J.; et al. Autonomous Braking of Host-Guest Nanoparticles for Enhanced Tumor Tissue Penetration and Retention. Small 2026, 22 (3), DOI: 10.1002/smll.202509060 


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